Alkaloids from Mongolian species of Peganum multisectum (Maxim) Bobrov
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چکیده
منابع مشابه
Agrobacterium Rhizogenes-mediated Transformation of Peganum multisectum (Maxim) Bobrov and Harmine Production in Hairy Roots
Using Agrobacterium rhizogenes due to create hairy roots is a useful method to product secondary metabolites in many medicinal plants. The transgenic hairy roots were induced from Peganum multisectum (Maxim) Bobrov a medicinally important species, by infecting leaf and stem explant with wild type Agrobacterium rhizogenes strain ATTCC 15834, which led to the induction of hairy roots from 19% of ...
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ETHNOPHARMACOLOGICAL RELEVANCE Peganum harmala is used in traditional medicine to treat a number of diseases including cancer. Our preliminary studies show that the alkaloidal extract of PH seed is cytotoxic to several tumor cell lines in vitro and has antitumor effect in a tumor model in vivo. The present investigation was aimed at extending our previous studies in identifying the components i...
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Bioactivity-guided fractionation was used to determine the cytotoxic alkaloids from the toxic plant Peganum harmala. Two novel indole alkaloids, together with ten known ones, were isolated and identified. The novel alkaloids were elucidated to be 2-(indol-3-yl)ethyl-α-L-rhamnopyranosyl-(1 → 6)-β-D-glucopyranoside (2) and 3-hydroxy-3-(N-acetyl-2-aminoethyl)-6-methoxyindol-2-one (3). The cytotoxi...
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Nine alkaloids with three different structural skeletons were isolated from Dicranostigma leptopodum (Maxim.) Fedde (Papaveraceae) by repeated silica gel column chromatography. Their chemical structures were identified on the basic of physicochemical and spectroscopic data. Among them, 10-O-methylhernovine (1), nantenine (2), corytuberine (3), lagesianine A (4), and dihydrocryptopine (9) were f...
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Introduction: peganum harmala L. (Zygophyllaceae) and varthemia persica DC (Compositeae) were used for co-culture studies. P.harmala was found to be one of the richest natural sources of β-carboline alkaloids. β-carboline alkaloids posses different neuropharmacologic activities including BDZ antagonism, MAOinhibitor and aminoreuptake inhibitor. The production of β-carboline alkaloids in cell ...
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ژورنال
عنوان ژورنال: Mongolian Journal of Chemistry
سال: 2016
ISSN: 2414-0082,2226-6739
DOI: 10.5564/mjc.v16i0.668